Evening Primrose Oil Beneficial

Evening Primrose Oil Beneficial
Research has also shown GLA in evening primrose oil to be beneficial for a number of other conditions including:

* arthritis, especially rheumatoid arthritis, where studies with GLA in evening primrose oil show significant improvement in joint stiffness, swelling, and overall discomfort
* cardiovascular conditions such as hypertension and high blood cholesterol
* diabetic neuropathy
* improved immune function
Supplementing with GLA in evening primrose oil can help restore the youthfulness of skin and hair as well as help improve general well-being.

* asthma
* allergies
* obesity
* multiple sclerosis
* hyperactivity
* premenstrual syndrome

In some studies, evening primrose oil has been shown to:

* increase the desirable anti-inflammatory prostaglandin E1 series
* help restore the gastrointestinal lining & heal ulcerations (improving nutrient absorption & food intolerance)
* help with autoimmune diseases (including Lupus and Crohn's disease)
* benefit fibrocystic breast disease
* benefit diabetic neuropathy
* reduce symptoms of alcohol withdrawal and help prevent liver & central nervous system damage from alcohol
* potentiate insulin effects
* increase feelings of well-being

Overall, evening primrose oil is an extremely valuable natural health supplement with many health benefits.
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Why evening primrose oil works

Why evening primrose oil works

Evening primrose oil provides a pure dose of gamma linoleic acid (GLA), which has few sources in nature. So here is the tale of the brambly thicket in the Hormone Jungle known as "prostaglandins," hormone-like chemicals that have very short lives and very large local effects.
To make prostaglandins, you need essential fatty acids--"essential" because our bodies don't make them so we have to eat them. There are two kinds of essential fatty acids that are important here--omega 6 fatty acids and omega 3 fatty acids. We need both kinds to be healthy. A lot has been written lately about omega 3 fatty acids, which come from fish, but omega 6's are even more important. The essential fatty acid in the omega 6 family is linoleic acid (LA). After we eat LA, an enzyme (delta 6 desaturase, for you biochemistry groupies) shows up and changes LA into a new form, GLA. That evolves into DGLA, which hovers in indecision, sniffing the bloodstream for omega 3 fatty acids. If it finds omega 3's, it becomes our hero, prostaglandin 1. If DGLA finds no omega 3's, it becomes arachidonic acid (AA), which becomes the villain--prostaglandin 2, which clots the blood, creates inflammation, makes stress reactions worse, and plays a role in causing endometriosis.(7, 10)

So, prostaglandin 1 is good because it prevents inflammation, stops cells from multiplying (as in endometriosis and cancer), and blocks prostaglandin 2 production(44). It also prevents blood clots, lowers cholesterol, reduces blood pressure, fixes defective T-lymphocyte immune cells (important for cancer , allergies, and infections), and maintains salt and water balance, nerve conduction, and gastrointestinal function.(3, 5)

Doctors have thought this was interesting as biochemistry but irrelevant for patients because an average American eats 10 times more LA than needed.(44) We couldn't possibly be deficient.

Prostaglandin 1 constantly breaks down so it has to be replaced all the time.(4). Some people are born with limited ability to make the enzyme, some people don't give it the right kinds of fat to use, and some have a wide range of medical conditions that block it. evening primrose oil

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Evening Primrose Oil Interactions with Herbs and Dietary Supplements

Evening Primrose Oil Interactions with Herbs and Dietary Supplements
In animal studies, gamma-linolenic acid (an ingredient of evening primrose oil) is reported to lower blood pressure. Theoretically, evening primrose oil may have additive effects when taken concomitantly with thyme, because a fixed combination of thyme fluid extract and primrose root tincture (Bronchicum Tropfen) has been used in studies to treat bronchitis.
Primrose oil may potentially interact with herbs and supplements used to treat arthritis, gastrointestinal disorders, obesity, seizures, viral infections, and psychosis. Antineoplastics may also interact with evening primrose oil.
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Evening Primrose Oil Interactions with Drugs

Evening Primrose Oil Interactions with Drugs

Because of reported seizures in people taking evening primrose oil alone or in combination with certain medications used to treat mental illness, patients should use caution when combining evening primrose oil with medications like chlorpromazine (Thorazine®), thioridazine (Mellaril®), trifluoperazine (Stelazine®), or fluphenazine (Prolixin®). In people with a history of seizures, doses of anti-seizure medications may require adjustment because evening primrose oil may increase the risk of seizures.

An ingredient of evening primrose oil, gamma-linolenic acid, is reported to lower blood pressure in animal studies. Although human studies do not show clear changes in blood pressure, people taking certain blood pressure medications should consult with a healthcare professional before starting evening primrose oil.

Possible additive effects may occur when evening primrose oil is taken with anticoagulants (blood thinners) and drugs used to treat arthritis.

Interactions may also occur with the following: antineoplastic agents, anti-obesity agents, antiviral agents, CNS stimulants, drugs metabolized by the liver, gastrointestinal treatments, and neurological agents.
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Evening Primrose Oil Side Effects and Warnings

Evening Primrose Oil Side Effects and Warnings
Several reports describe seizures in individuals taking evening primrose oil (EPO). Some of these seizures developed in people with a previous seizure disorder, or in individuals taking evening primrose oil in combination with anesthetics. Based on these reports, people with seizure disorders should not take EPO. Evening primrose oil should be used cautiously with drugs used to treat mental illness such as chlorpromazine (Thorazine®), thioridazine (Mellaril®), trifluoperazine (Stelazine®), or fluphenazine (Prolixin®), due to an increased risk of seizure. Other reports describe occasional headache, abdominal pain, nausea, and loose stools in people taking evening primrose oil . In animal studies, gamma-linolenic acid (an ingredient of evening primrose oil) is reported to decrease blood pressure.

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Evening Primrose Oil Precautions:

Evening Primrose Oil Precautions:

Evening Primrose Oil is generally safe when used in recommended dosages. Reported side effects are rare and mild, and include nausea, stomach pain, and headache. Stomach pain and loose stools may be indications that the dosage is too high.

Omega-6 supplements, including GLA and EPO, should not be used if you have a seizure disorder because there have been reports of these supplements inducing seizures.

EPO should not be taken if you have bleeding problems or a blood disorder.

Taking EPO while breastfeeding is considered safe as breast milk actually contains both LA and GLA.
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What's Evening Primrose Oil Made Of

What's Evening Primrose Oil Made Of?:

Evening Primrose Oil is extracted from the seeds and prepared as medicine using a chemical called hexane. The seeds contain up to 25% essential fatty acids including linoleic acid (LA) and gamma-linolenic acid (GLA). Both LA and GLA belong to the omega-6 family of fatty acids. The vast majority of North Americans get too much omega-6 fatty acid in their diet. However, there are different types of omega-6 fatty acids. Some are health promoting, such as those found in evening primrose oil (EPO), while others can be more harmful, such as those typically found in the standard American diet. The body needs a balance of omega-3 and omega-6 fatty acids to function normally. Omega-3 oils can be found in cold water fish such as salmon, as well as some plant sources, or in dietary supplements.

Other sources of GLA include spirulina (a blue-green algae), borage, hemp, and black currant oils.
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