More than 30 human studies report the benefits of Evening Primrose Oil for eczema and dermatitis. A study of 1,207 patients found that EPO helped relieve symptoms from skin conditions, including itching, crusting, edema (fluid, swelling), and redness. EPO can be used in children and adults with skin conditions.
Premenstrual syndrome (PMS)
In one review of 10 studies that used EPO to treat PMS, only two were well designed. Both of those studies found that EPO had no effect on PMS symptoms. Rheumatoid arthritis (RA)
Although a few studies have found that people with RA who took Evening Primrose Oil felt better, the studies were hampered by poor design and high drop-out rates. Rheumatoid arthritis should be treated with conventional medications, to slow down or stop permanent joint damage.
Raynaud' s phenomenon
One small study suggests that taking EPO may help reduce symptoms in some people with Raynaud' s phenomenon. More studies are needed.
Diabetic peripheral neuropathy
Diabetic peripheral neuropathy is a nerve condition where people with diabetes have numbness, tingling, pain, burning, or lack of sensation in their feet and legs. Two studies have found that GLA may help reduce symptoms of diabetic neuropathy.
Although there is not a lot of scientific evidence, Evening Primrose Oil is widely used to treat breast pain (mastalgia) in a number of European countries. A few studies have found that EPO seemed to help, but they have not been well-designed studies. Other studies show no benefit.
Although Evening Primrose Oil has gotten popular for treating hot flashes, there is no scientific evidence that it actually helps.